Metabolic health is a topic increasingly coming to the forefront. Not only because of the rising prevalence of insulin resistance, but also due to efforts toward healthy weight loss without extreme diets.
This is why modern nutritional supplements targeting glycemic response, insulin sensitivity and energy metabolism are becoming popular. One of them is Skeeneffect Natural Metabolic Health — a complex designed to support metabolism from multiple directions at once.
While most users observe improved appetite control, more even energy and gradual weight reduction, a small portion of people may experience increased appetite in the first days or weeks..
At first glance, this may seem contradictory. Why would a supplement intended to support metabolic balance cause hunger? The explanation is logical and based on biochemical processes in the body.
A restart of insulin sensitivity can temporarily increase hunger
In people with reduced insulin sensitivity, glucose remains in the bloodstream longer. When the combination of ingredients such as white mulberry extract, reduced glucose absorption from food or supported metabolic signaling pathways begins to work, cell sensitivity improves. Glucose moves into the cells more quickly.
However, the brain may interpret this in the short term as: "energy is dropping, I need to refuel". Thus, appetite will increase for a while while the body adapts to the new, more efficient functioning.
Stabilizing glycemia disrupts glucose cycles the body was used to for years
Many people function in a glycemic cycle of: sweet = quick energy, followed by a sharp drop culminating in cravings for more sweets.
But this is a learned mechanism, not a biological need.
Skeeneffect Metabolic Health gradually mellows out these glycemic swings.However, in the first days the body may react with increased hunger because it no longer receives the extreme glucose spikes it was used to. Adaptation takes time, similar to reducing caffeine intake.
AMPK activation increases cellular energy demands
AMPK is an enzyme that acts as a metabolic sensor. When activated, it:
- increases energy burning,
- supports fat oxidation,
- improves cellular energy efficiency,
- reduces glucose storage as fat.
In the initial phase, this activation may raise energy expenditure,which can manifest as a mild feeling of hunger — especially in people who normally eat little protein or have long breaks between meals.
Low protein and fibre intake can intensify subjective hunger
The most common factor behind increased appetite during metabolic supplementation is improper meal composition. Lack of protein, low fibre intake, a high share of fast carbohydrates and skipping breakfast increase the hunger hormone ghrelin.
When ghrelin rises, the brain receives the signal “I’m hungry, I need to eat.” Diet therefore determines how much ghrelin the body produces — not the supplement.
Temporary signals of shifting energy balance
If the body is used to a “saving mode” (low energy expenditure, fatigue, slow metabolism), activation of metabolic pathways may temporarily increase appetite.
This is similar to when a person becomes active again after a long period of low physical activity. Energy demand shifts. This usually settles within 5–14 days.
Psychological factor: expectations vs. reality
Some users expect the supplement to immediately suppress hunger, accelerate metabolismwithout any dietary changes and trigger automatic weight loss.
These expectations are influenced by the trend of GLP‑1 analogues, which drastically
reduce appetite.
Metabolic Health, however, is not a GLP‑1 agonist. Its role is harmonizing metabolism, not
shutting down biological signals.
Hunger may sometimes simply be a byproduct of the body interpreting its signals more accurately.
Why can bloating occur?
Skeeneffect Natural Metabolic Health reduces glycemic fluctuations. When they decrease, digestion may slow temporarily.This increases food fermentation and may cause fullness or bloating by reducing the supply of rapidly available glucose to the gut microbiome.
Gut bacteria must shift to another energy source, resulting in:
- slightly increased gas production,
- a feeling of bloating,
- temporary discomfort.
Microbiome adaptation is a common response to metabolic changes. Plant extracts may gently slow or speed peristalsis. For some people this causes bloating until digestion stabilizes.
How to minimize increased appetite and reduce bloating during adaptation?
These symptoms are not a reason to stop supplementation. Based on customer feedback and biochemical mechanisms, the most effective approaches include:
- taking Skeeneffect Metabolic Health with food rather than on an empty stomach, počas jedla, nie nalačno,
- adding breakfasts containing 20–25 g of protein,
- adding fibre to meals,,
- taking a short walk after lunch (10–15 minutes),
- drinking enough water,
- avoiding long gaps between meals.
The body adapts quickly to the new metabolic rhythm. For most people, adaptation is short — usually 3 to 7 days, up to 14 days.
Short‑term increases in appetite or mild bloating are not side effects but physiological adaptationadaptation, showing that metabolic pathways are moving toward balance. These natural adaptation mechanisms reflect the the body learning to function more efficiently,with better insulin sensitivity, more stable glycemia and more active metabolic pathways.
In most cases, cases, this effect fades within a few days and is followed by the main benefits such as stabilized appetite, improved digestion, more even energy, gradual weight reduction and harmonized glycemia.
