{"id":21276,"date":"2024-02-20T16:21:52","date_gmt":"2024-02-20T15:21:52","guid":{"rendered":"https:\/\/skeeneffect.sk\/?p=21276"},"modified":"2024-02-28T13:38:16","modified_gmt":"2024-02-28T12:38:16","slug":"terapia-retinoidmi-a-s-nou-suvisiace-problemy-existuje-vhodna-alternativa","status":"publish","type":"post","link":"https:\/\/skeeneffect.sk\/en\/terapia-retinoidmi-a-s-nou-suvisiace-problemy-existuje-vhodna-alternativa\/","title":{"rendered":"Retinoid therapy and its associated problems: is there a suitable alternative?\u00a0"},"content":{"rendered":"
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Side effects associated with the use of retinoids are often related to skin irritation. This is manifested by erythema, scaling, burning and itching. These symptoms are typical of retinoid dermatitis. It occurs in approximately 92 % of all patients, which significantly limits retinoid treatment.<\/strong><\/h6>\n<\/div>\n<\/div>\n\n\n\n
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What is retinoid therapy used for? These are molecules that serve to penetrate the deeper layers of the skin. As a result, there should be an\u00a0overall improvement in the skin, a reduction in pigmentation and fine lines<\/strong>. Retinoids are also used to stimulate the natural production of collagen and elastin in the skin, which prevents the skin from losing its elasticity. These substances are also used in people suffering from acne, as their effects include the prevention of clogging of pores and modification of sebum production.\u00a0<\/p>\n\n\n\n

RETINOIDS BRING PROBLEMS<\/h2>\n\n\n\n

Most patients report an unpleasant burning sensation when exposed to heat, or photosensitivity - that is, sensitivity to the sun. These patients should be instructed to avoid the sun or use sunscreen<\/strong>In some cases, conjunctival irritation is also observed when retinoids are used near the eyes. Thus, these substances are not considered safe and, from the point of view of use, bring a number of adverse effects. These have been confirmed in patients of different age groups, with different skin problems. <\/p>\n\n\n\n

RISK TO PREGNANT AND BREASTFEEDING WOMEN<\/h2>\n\n\n\n

Because of their teratogenic and embryotoxic potential, pregnant or lactating women should use topical retinoids with caution, despite their very low (5-8 %) absorption. As these effects are dose-dependent, patients should be advised to reduce the dose<\/strong> and frequency in case of intense manifestations. This dose reduction will naturally reduce the efficacy of the treatment. <\/p>\n\n\n\n

Remember<\/em><\/strong>The routine use of steroids to relieve symptoms may have side effects when used over a long period of time.<\/em><\/p>\n\n\n\n

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OTHER ADVERSE EFFECTS<\/h3>\n\n\n\n

Temporary, mild worsening of acne blisters in the first two weeks of use<\/strong>, hyperpigmentation and increased telangiectasia (dilated capillaries on the skin surface) are other commonly identified adverse effects of retinol.<\/p>\n\n\n\n

WHAT ARE SUITABLE ALTERNATIVES TO RETINOID THERAPY?<\/h2>\n\n\n\n

In view of these adverse effects in the use of cosmetic products, alternative therapeutic agents to retinoids offer significant opportunities for the market. One such substance is Revinage\u00ae<\/strong>, a component of Skeeneffect Ageless Cream<\/a>.<\/p>\n\n\n\n

THE UNIQUENESS OF THE PIC\u00c3O PLANT, THEREFORE, ITS FLOWERS AND FRUITS <\/h3>\n\n\n\n

Pic\u00e3o Preto has recently been the subject of scientific research that has supported its use in herbal and folk medicine<\/strong>. In folk medicine, it is traditionally used for its anti-inflammatory, diuretic, antirheumatic and antidiabetic properties.<\/p>\n\n\n\n

EFFECTIVE COMPOSITION<\/h3>\n\n\n\n

The phytochemical composition of Bidens pilosa is diverse, characterized, above all, , by the presence of flavonoids, terpenes, phenylpropanoid compounds<\/strong>, lipids and benzenoids. One of the main chemical constituents of Bidens pilosa is a phytol, a diterpene present as part of the chlorophyll pigment.<\/p>\n\n\n\n

Some studies show that Phytol excels by being oxidized to phytanic acid<\/strong> (also present in Bidens pilosa) during metabolism. The latter is able to bind to RXR receptors and activate them as retinoids and their derivatives at very low concentrations. In addition, it also stimulates the transcriptional activity of RAR18, thus acquiring retinol-like properties.<\/p>\n\n\n\n

WHAT ARE THE MAIN BENEFITS OF REVINAGE\u00ae?<\/h3>\n\n\n\n