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Joint nutrition

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Premium joint nutrition for an active lifestyle. Pain-free movement. Recovery without compromise.

Our joint nutrition was designed for people who want to stay active at any age – whether they play sports, do physical work, or want to maintain joint flexibility and health.

We combine cutting-edge bioactive peptides, natural extracts, and minerals that target all key factors of joint health: cartilage nutrition, joint lubrication, tissue regeneration, and inflammation reduction.

Our advice: Best results are achieved with consistent daily use for at least 3-6 months.
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SYNOVIALIS ACTIVE 18+ Y

SYNOVIALIS ACTIVE KIDS 10+ Y

SYNOVIALILS ACTIVE COMBO

COMPLEX EFFECTS

We combine cutting-edge bioactive peptides, natural extracts, and minerals that target all key factors of joint health.

EASY TO USE

The instant drink has a pleasant taste, dissolves easily, and thanks to its single-serving packaging, you can conveniently take it with you anywhere.

INNOVATIVE MOLECULES

SYNOVIALIS ACTIVE contains modern and intelligent complexes of active ingredients. Thanks to them, joint mobility is improved.

CLINICALLY TESTED

The individual ingredients of the product have been thoroughly scientifically tested, and their positive effects are confirmed by prestigious clinical studies. We guarantee high effectiveness.

DEVELOPED IN SLOVAKIA

This product is developed and manufactured in Slovakia.

Comprehensive support for your body

Why choose SYNOVIALIS ACTIVE?

Our joint nutrition was designed for people who want to stay active at any age – whether they play sports, do physical work, or want to maintain joint flexibility and health. The product is intended for both active and recreational athletes, people with physically demanding jobs, and anyone who wants to preserve joint flexibility and health.

  • Supports the strength and flexibility of cartilage.
  • Increases joint lubrication and mobility.
  • Relieves inflammation and pain naturally.
  • Accelerates recovery after sports activity.
  • Protects cells from oxidative stress.
  • Premium taste with natural orange flavour.
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Comprehensive support for your body

Who is SYNOVIALIS ACTIVE for?

  • Active people and athletes.
  • Adults with excessive joint strain.
  • Anyone who wants to prevent cartilage wear and improve quality of movement.

Give your body the care it deserves - naturally and with respect for its needs.

Scientifically backed natural ingredients

Why is SYNOVIALIS ACTIVE so effective?

The revolutionary natural formula for a healthy metabolism combines 4 key natural ingredients whose effectiveness is confirmed by scientific studies. Each contributes to your metabolic health in a different, unique way.

Naticol® x3PEPTIDE™

Patented hydrolyzed marine collagen with a precisely defined profile of bioactive peptides (containing up to 25% tripeptides). Thanks to its low molecular weight (≈1,200 Da), it is rapidly absorbed and specifically stimulates cartilage cells (chondrocytes) and bone-forming cells (osteoblasts). Clinical studies have demonstrated stimulation of endogenous type II collagen synthesis, improvement in joint health, and a slowdown in joint aging processes.

Ovomet®

Ovomet® is a natural source of type I, V, and X collagen derived from the eggshell membrane, specifically designed to support joint health and mobility. In addition to collagen, it naturally provides a rich matrix of biomolecules, including hyaluronic acid, elastin, chondroitin sulfate, and glucosamine, all of which play a key role in maintaining healthy joints, reducing discomfort, and promoting flexibility.

MovePLX®

MovePLX® is a plant extract derived from lemon verbena (Aloysia citrodora) leaves, supported by clinical studies demonstrating its ability to accelerate recovery after physical exercise. Its patented extraction process ensures one of the purest verbascoside-rich ingredients available on the market. MovePLX® is a unique ingredient designed for physically active individuals, helping to enhance muscle recovery, reduce oxidative stress, and alleviate post-exercise fatigue.

Boswellin ® WS

Boswellia serrata extract, a plant-derived ingredient rich in boswellic acids. These active compounds can inhibit the enzyme 5-lipoxygenase (5-LOX), which is involved in the production of pro-inflammatory mediators in the body. As a result, Boswellia naturally helps reduce inflammation and alleviate pain, supporting overall joint comfort and mobility.

C3 Reduct®

Turmeric (Curcuma longa) extract in the form of tetrahydrocurcuminoids is a highly bioavailable form of curcumin. It exhibits potent antioxidant properties and provides anti-inflammatory benefits, helping to protect cells from oxidative stress and support a healthy inflammatory response.

Others

Hyaluronic acid, vitamin C, zinc, manganese.

WHAT CAN YOU EXPECT FROM TAKING SYNOVIALIS ACTIVE?

  • Fast onset of action, with reduced joint pain in as little as 5 days. After 30 days, pain is reduced by 47%, and after 9 weeks by 78%. 
  •  Joint stiffness is reduced by 43% after 30 days. 
  • Cartilage dysfunction is reduced by 39% after 30 days. 
  • Reduction of inflammatory markers responsible for cartilage degradation by 37%.
  • Improved recovery through enhanced sleep quality (34% reduction in anxiety and a 44% reduction in the number of days with interrupted sleep per week). 
Scientifically proven effectiveness of natural ingredients

CLINICAL STUDIES

  1. Lacey S, and al. (2019) JOJCS.MS.ID.555783
  2. S. M Tyree and al. (2021) JOJCS.MS.ID.555850
  1. Aguirre A., Gil-Quintana E., Fenaux M., Erdozain S. and La Nuez M. Effects of 50 days of OvometR supplementation on biomechanical parameters and subjective pain perception among old institutionalized patients. A preliminary study. Journal of Osteoporosis and Physical Activity 5 (2017 a): 1.
  2. Aguirre A., Gil-Quintana E., Fenaux M., Erdozain S. and La Nuez M. Effects of 50 days Eggshell membrane OvometR supplementation on biomechanical parameters and subjective pain perception among Crossfit Athletes. A preliminary study. Journal of Trauma & Treatment 6 (2017 b): 2.
  3. Ahmed T.A.E., Suso H.P. and Hincke M.T. Experimental datasets on processed eggshell membrane powder for wound healing. Data in brief 26 (2019): 104457.
  4. Arden N. and Nevitt M.C. Osteoarthritis: Epidemiology. Best Practice and Research: Clinical Rheumatology 24 (1) (2006): 15-26.
  5. Bhattaram P. and Chandrasekharan U. The joint synovium: a critical determinant of articular cartilage fate in inflammatory joint diseases. In Seminars in Cell and Developmental Biology Academic Press 62 (2017): 86-93.
  6. Blasco J.M.I., Aguirre A., Gil-Quintana E. and Fenaux M. The Effect of Daily Administration of 300 mg of Ovomet R for Treatment of Arthritis in Elderly Patients. International Journal of Clinical Rheumatology 11 (5) (2016): 077-081.
  7. Brecht M., Mayer U., Schlosser E. and Prehm P. Increased hyaluronate synthesis is required or fibroblast detachment and mitosis. Biochemical Journal 239 (1986): 445–450.
  1. Funes L. et al. “Effect of lemon verbena supplementation on muscular damage markers, proinflammatory cytokines release and neutrophils’ oxidative stress in chronic exercise”. Eur. J. Appl. Physiol. 2011; 111(4):695-705.
  2. Carrera-Quintanar L et al. “Antioxidant effect of lemon verbena extracts in lymphocytes of university students performing aerobic training program”. Scand. J Med. Sci. Sports. 2012; 22 (4):454-61.
  3. Carrera-Quintanar L et al., “Effect of polyphenol supplements on redox status of blood cells: a randomized controlled exercise training trial”. Eur. J Nutr. 2015 Oct;54(7):1081-93.
  4. Martinez-Rodriguez A et al. “Biochemical and psychological changes in university students performing aerobic exercise and consuming lemon verbena extracts”. Current Topics in Nutraceutical Research. 2015, Vol.13 Issue 2, p95-102.
  5. Caturla N, et al. “A randomized, double-blinded, placebo-controlled study of the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management”. J. Altern. Complement. Med. 2011; 17 (11):1051-63
  1. Aharony D and Stein RL. Kinetic mechanism of guinea pig neutrophil 5-lipoxygenase. J Biol Chem. 1986;261:11512-9
  2. Ford-Hutchinson AW, Gresser M, Young RN. 5-Lipoxygenase. Ann Rev Biochem. 1993;63:383-417
  3. Mogana R, Teng-Jin K, Wiart C. Anti-Inflammatory, Anticholinesterase, and Antioxidant Potential of Scopoletin Isolated from Canarium patentinervium Miq. (Burseraceae Kunth). Evidence-Based Complementary and Alternative Medicine. 2013;2013:article ID 734824:1-7
  4. Lee WL, Downey GP. Leukocyte elastase: physiological functions and role in acute lung injury.Am J Respir Crit Care Med. 2001 Sep 1;164(5):896-904
  5. Shah BA, Qazi GN, Taneja SC. Boswellic acids: a group of medicinally important compounds. Nat. Prod. Rep. 2009, 26, 72-89
  6. Tausch L, Henkel A, Siemoneit U, Poeckel D, Kather N, Franke L, Hofmann B, Schneider G, Angioni C, Geisslinger G, Skarke C, Holtmeier W, Beckhaus T, Karas M, Jauch Jand Werz O. Identification of Human Cathepsin G As a Functional Target of Boswellic Acids from the Anti-Inflammatory Remedy Frankincense. J Immunol 2009; 183:3433-42
  7. Ota M, Houghton PJ. Boswellic acids with acetylcholinesterase inhibitory properties from frankincense. Natural Product Communications. 2008;3(1):21-6
  8. Henderson WR. The role of leukotrienes in inflammation. Ann Intern Med.1994;121:684-97
  9. Lau CK, Belanger PC, Dufresne C, Scheigetz J, Therien M, Fitzsimmons B, Young RN, et al. Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase. J Med Chem. 1992;35:1299-318
  10. Majeed M, Badmaev V, Gopinathan S, Rajendran R, Norton T, and Braly J. Boswellin® The Anti-inflammatory Phytonutrient. Nutriscience Publishers Inc., Piscataway, NJ. 1996
  11. Majeed M, Prakash L, Badmaev V, Nujoma Y, Natarajan S, Norton T, et al. Redefining Our Standards, Boswellin® The Only Natural Leukotriene and HLE Inhibitor®. 1999. Sabinsa Corporation
  12. Majeed M, Vaidyanathan P, Natarajan S, Shaheen M, Vuppala KK. Effect of Boswellin® Super on knee pain in Japanese adults: A randomized, double-bline, placebo-controlled trial. European Journal of Biomedical and Phamaceutical Sciences. 2016;3(10):293-298
  13. Natarahan S and Majeed M. To assess the efficacy & safety of NILIN™ SR tablets in the management of osteoarthritis of knee. Int J Pharm Life Sci. 2012 Feb;3(2):1413-23.
  14. Pang X, Yi Z, Zhang X, Sung B, Qu W, Lian X, et al. Acetyl-11-keto-beta-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis. Cancer Res. 2009;69(14):5893-900
  15. Park B, Prasad S, Yadav V, Sung B, Aggarwal BB. Boswellic acid suppresses growth and metastasis of human pancreatic tumors in an orthotopic nude mouse model through modulation of multiple targets. PLoS One.2011b;6(10):e26943
  16. Park B, Sung B, Yadav VR, Cho SG, Liu M, Aggarwal BB. Acetyl-11-keto-β-boswellic acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4 chemokine receptor expression. Int J Cancer. 2011a;129(1):23-33
  17. Safayhi H, Mack T, Sabieraj J, Anazodo MI, Subramanian LR, Ammon HPT. Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J PharmacolExpTher. 1992;261(3):1143-6
  18. Safayhi H, Rall B, Sailer ER, Ammon HP. Inhibition by boswellic acids of human leukocyte elastase. J Pharmacol Exp Ther. 1997;281:460-3.
  19. Sailer ER, Schweizer S, Boden SE, Ammon HP, Safayhi H. Characterization of acetyl-11-keto-β-boswellic acid and arachidonate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling. Eur J Biochem. 1998;256:364-8
  20. Sailer ER, Subramanian LR, Rall B, Hoernlein RF, Ammon HP, Safayhi H. Acetyl-11-keto-β-boswellic acid (AKBBA):structure requirements for binding and 5-lipoxygenase inhibitory activity. Br J Pharmacol. 1996;117:615-8
  21. Werz O, Szellas D, Henseler M, Steinhilber D. Nonredox 5-Lipoxygenase inhibitors require glutathione peroxidase for efficient inhibition of 5-lipoxygenase activity. Molecular Pharmacology.1998;54:445-51
  22. Yadav VR, Prasad S, Sung B, Gelovani JG, Guha S, Krishnan S, et al. Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers. Int J Cancer. 2012;130(9):2176-84

 

Product Daily dose: 1 sachet per day.

Reference Value %

NATICOL® x3PEPTIDE™2500 mg*
Vitamin C (acerola juice concentrate)100 mg100
MovePLX® (lemon verbena extract) 400 mg*
Ovomet® (eggshell membrane collagen)300 mg300 mg*
Sodium hyaluronate 100 mg*
Boswellin® (Boswellia serrata extract) 100 mg*
Curcumin C3 Reduct ® (turmeric extract) 100 mg*
Zinc (zinc bisglycinate).10 mg100
Manganese  *

*RI (Reference Intakes) is not determined for these ingredients

Recommended daily dosage:.  Take 1 sachet daily. Mix the contents of one sachet with approximately 150 mL of water and drink.  

INGREDIENTS: NATICOL® x3PEPTIDE™, natural orange flavour, lemon verbena extract, acerola juice concentrate, antioxidant, eggshell membrane collagen,  malic acid (acidity regulator), sodium hyaluronate, Boswellia serrata extract, turmeric extract, natural beta-carotene colour, steviol glycosides, zinc bisglycinate, manganese. 

Alergenes: Fish and fish-derived products, eggs and egg-derived products. 

WARNINGS

Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Keep out of reach of young children. Not intended for young children, pregnant women, or breastfeeding women. Store in a dry place at temperatures below 25°C. Protect from direct sunlight and frost.

Advice

QUESTIONS AND ANSWERS

This joint support supplement is suitable for people of all age groups, from active athletes and individuals with physically demanding jobs to seniors who wish to support the health of their musculoskeletal system. It is also recommended as a preventive measure for those exposed to long-term joint strain.

We recommend taking SYNOVIALIS ACTIVE as follows: a 6-month course, followed by a 1-2 month break. 

Joint support supplements do not work immediately, as cartilage regenerates slowly. We recommend taking the product for at least 3 months to achieve noticeable results. 

The best results are achieved with regular use for a minimum of 3 months.

Yes. This joint support supplement can be combined with common dietary supplements.

The product contains the following allergens: fish and eggs.

Yes. Athletes place increased demands on their musculoskeletal system. Joint support supplements help promote recovery, reduce the risk of injuries, and support long-term physical performance.

This product is generally intended for adults. For children, please use SYNOVIALIS ACTIVE KIDS.

Užívanie v tomto období konzultujte so svojím lekárom. Nie všetky zložky sú testované na bezpečnosť počas tehotenstva a dojčenia.

Áno. Mnohé látky ako kolagén, vitamín C či minerály sú prirodzenou súčasťou tela. Odporúča sa však robiť kúry a dať si medzi nimi prestávku 1–2 mesiace.

No. This joint support supplement is a dietary supplement. It supports the nutrition of joints and tendons but is not intended to treat or cure diseases. If you have a serious health condition, please consult a healthcare professional.

Follow the recommended dosage instructions provided on the packaging. For best results, take the product regularly, preferably with a meal and adequate fluid intake.

Didn't get the answer? Contact us.

Recenzie

NAŠICH ZÁKAZNÍKOV

Our products contain precisely mixed combinations of natural bioactive substances that affect many processes in the human body. Thanks to this, they can visibly improve the skin condition, slow aging, or alleviate the symptoms of diseases.

MUDr. Katarína Glombová

Our products contain precisely mixed combinations of natural bioactive substances that affect many processes in the human body. Thanks to this, they can visibly improve the skin condition, slow aging, or alleviate the symptoms of diseases.

MUDr. Katarína Glombová

Our products contain precisely mixed combinations of natural bioactive substances that affect many processes in the human body. Thanks to this, they can visibly improve the skin condition, slow aging, or alleviate the symptoms of diseases.

MUDr. Katarína Glombová

Our products contain precisely mixed combinations of natural bioactive substances that affect many processes in the human body. Thanks to this, they can visibly improve the skin condition, slow aging, or alleviate the symptoms of diseases.

MUDr. Katarína Glombová

Our products contain precisely mixed combinations of natural bioactive substances that affect many processes in the human body. Thanks to this, they can visibly improve the skin condition, slow aging, or alleviate the symptoms of diseases.

MUDr. Katarína Glombová

Our products contain precisely mixed combinations of natural bioactive substances that affect many processes in the human body. Thanks to this, they can visibly improve the skin condition, slow aging, or alleviate the symptoms of diseases.

MUDr. Katarína Glombová

BLOG

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MovePLX® - the effective ingredient that changes the rules

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SYNOVIALIS ACTIVE: Joint nutrition that gives you extra value over conventional products on the market

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