
The natural ingredient Boswellin® is not just a traditional extract from the frankincense tree. It is a modern, standardized preparation whose effectiveness has been backed by scientific research.
Inflammation is the body's natural response, but when it becomes chronic, it leads to pain, tissue damage and diseases such as arthritis and joint degeneration. The traditional resin from the Boswellia serrata tree has been used in Ayurveda for thousands of years, and modern science confirms its effects. The patented Boswellin® extract ranks among the best researched natural anti- inflammatory solutions.
Boswellin® is a great warrior for inflammatory problems, joint pain or cartilage degeneration. Its ability to dampen inflammation on multiple levels and protect connective tissue makes it a powerful ally in the fight against joint pain, arthritis and other inflammatory processes.
Its effect is built more on prevention and promoting regeneration than on quick, immediate relief. That's why consistent and regular use is key.
How does Boswellin® work and what happens in the body with regular use?
1. Inhibition of 5-lipoxygenase (5-LOX)
Boswellic acids block the activity of 5-lipoxygenase, leading to reduced production of leukotrienes - substances that promote inflammation and are associated with pain and swelling.
Studies by Safayhi et al. (1992) and Sailer et al. (1996, 1998) have shown that acetyl-11-keto-β- boswellic acid (AKBA) is a specific and potent inhibitor of 5-LOX.
2. Inhibition of white blood cell elastase
Boswellic acids also inhibit the enzyme elastase, which degrades connective tissue and cartilage. Boswellias help reduce oxidative stress that occurs with inflammation and tissue damage. This helps protect cartilage and joints from degeneration.
As a result, joints are protected from degeneration (Safayhi et al. 1997; Tausch et al. 2009).
3. Anti-inflammatory and antioxidant action
In addition to leukotrienes, boswellia affects other chemicals produced by the body during inflammation, such as cytokines (e.g., TNF-α, IL-1β, IL-6). Reducing these substances helps to reduce the inflammatory process (Shah et al. 2009).
They also reduce oxidative stress, which accelerates cell and tissue damage.
4. Anti-cancer potential
- Some boswellic acids have demonstrated the ability to suppress angiogenesis - the formation of new blood vessels that nourish tumor and the invasiveness of tumor cells.
Studies by Pang et al. (2009), Park et al. (2011), Yadav et al. (2012).
5. Protection of cartilage and connective tissues
Boswellia extracts support the maintenance of cartilage integrity by slowing the degradation of collagen and proteoglycans.
They may also promote the repair of moderately damaged structures, or at least slow their deterioration.
What are the results of clinical studies with Boswellin®?
Clinical studies show that people with arthritis or other inflammatory joint conditions have experienced a reduction in pain and improvement in mobility after 4-8 weeks of taking standardized Boswellia extracts.
Some studies suggest that combining boswellia with other anti-inflammatory supplements such as
curcumin may have a synergistic effect.
What have clinical studies looked at?
- Osteoarthritis and knee pain.A randomized, double-blind, placebo-controlled study in Japan (Majeed et al. 2016) showed that taking Boswellin® significantly reduced knee pain and improved mobility after just 4 weeks.
- Safety and efficacy with long-term use.Natarahan & Majeed (2012) confirmed that Boswellin® is safe even when administered long-term to patients with knee osteoarthritis.
- Anti-inflammatory activity.Already in the 1990s (Majeed et al. 1996, 1999), Boswellin® was presented as the only natural inhibitor of both leukotrienes and human elastase, which distinguishes it from other plant extracts.
However, unlike analgesics or strong anti-inflammatory drugs, Boswellin does not act immediately. This is for several reasons.
- Organic inflammation and connective tissue damage do not happen overnight. That's why they also take time to recover.
- The effect is accumulative - regular use of the extract is necessary to sufficiently suppress the production of inflammatory substances and for the regenerative processes to take effect.
- Individual differences in genetics, metabolism, joint load, diet and other factors influence how quickly a person feels relief.
Why is Boswellin® unique?
- It has a dual effect - it counteracts both leukotrienes and elastase.
- Standardized formulation - the content of active boswellic acids is guaranteed.
- Clinically proven effects - several high-quality studies have confirmed its effectiveness for joint pain and inflammation.
You will find this active ingredient together with other natural substances in our SYNOVIALIS ACTIVE 18+ Y PREMIUM JOINT NUTRITION FOR ACTIVE LIFE - a complex collagen for adults that
works on several levels at once.